The Safer COVID-19 Response checklist has been produced for managers of health-care services, individual practitioners and health policymakers worried about the impact of violence against health-care workers, facilities and patients during the COVID-19 response. It provides a practical, actionable summary of important measures for preventing, reducing and mitigating the effects of violence against health-care workers and patients during the COVID-19 response. It also contains a series of online references to help understand and implement these measures. This checklist aims to encourage local risk assessment, informed response measures and accountability and transparency towards those receiving care as a means of preventing violence against health-care workers and services. We aim to protect health-care workers’ well-being and ensure that they apply the ethical principles of health care.